Jose Luis Turabian*
Citation: Turabian JL. Incidence Rates and Risk Factors for Covid-19 Booster Adverse Reactions in General Medicine. Medp Public Health Epidemiol. 2022; 1(1): mpphe-202210007.
Abstract
Background: Data on the incidence rate and risk factors of covid-19 booster adverse
reactions are critical to success vaccination programs.
Objective: To describing the incidence rates and risk factors for covid-19 booster adverse
reactions in general medicine.
Methodology: An observational, longitudinal and prospective study of patients who self report covid-19 booster adverse reactions as a reason for visiting in a general medicine office in
Toledo (Spain) was carried out from December 1, 2021-September, 1 2022.
Results: Statistically significant factors found for the covid-19 booster adverse reactions
were: 1) Protective factors: age > = 65 years, complex family, chronic diseases of circulatory
system, and vaccine booster with Comirnaty, Pfizer / BioNTech); And 2) Risk factors: age 14-
64 years, presence of chronic diseases, chronic diseases of genitourinary, and vaccine booster
with Moderna mRNA-1273. The incidence rates of covid-19 booster adverse reactions were: 2%
>=14 years, 0.3% >= 65 years, 3% in women, 1.5% in men, 1% in Comirnaty (Pfizer / BioNTech),
and 3 % in Moderna mRNA-1273.
Conclusions: In the context of general medicine in Toledo (Spain), for the period December
1, 2021-September, 1 2022, the incidence rates of covid-19 booster adverse reactions was low,
especially in >= 65 years and men. Risk factors focus on women aged 16-64 years, with chronic
diseases, and vaccine booster with Moderna mRNA-1273. The risk estimates clearly favour
vaccination. However, the small number of cases limits the conclusions that can be drawn.
Key Words: COVID-19; SARS-CoV-2; Post-Vaccination Reactions; COVID-19 vaccines; Adverse
Events Reaction; Booster Vaccination; General Practice; Risk Factors
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